Born Erick Lee Purkhiser, Interior started the Cramps in 1972 with guitarist Poison Ivy (born Kristy Wallace, later his wife) whom, as legend has it, he picked up as a hitchhiker in California. By 1975, they had moved to New York, where they became an integral part of the burgeoning punk scene surrounding CBGBs.

Their music differed from most of the scene's other acts in that it was heavily steeped in camp, with Interior's lyrics frequently drawing from schlocky B-movies, sexual kink and deceptively clever puns. (J.H. Sasfy's liner notes to their debut EP memorably noted: "The Cramps don't pummel and you won't pogo. They ooze; you'll throb.") Sonically, the band drew from blues and rockabilly, and a key element of their sound was the trashy, dueling guitars of Poison Ivy and Bryan Gregory (and later Kid Congo Powers), played with maximal scuzz and minimal drumming.